{"id":236998,"date":"2026-01-15T07:06:08","date_gmt":"2026-01-15T03:06:08","guid":{"rendered":""},"modified":"-0001-11-30T00:00:00","modified_gmt":"-0001-11-29T20:00:00","slug":"","status":"publish","type":"post","link":"https:\/\/ucnoqta.az\/?p=236998","title":{"rendered":"Di\u015fl\u0259ri qorumaq \u00fc\u00e7\u00fcn t\u0259bii mexanizm"},"content":{"rendered":"

T\u0259dqiqatç\u0131lar insan tüpürc\u0259yind\u0259 olan t\u0259bii amin tur\u015fusu olan arginin di\u015f lövh\u0259sinin aqressiv xüsusiyy\u0259tl\u0259rini z\u0259ifl\u0259d\u0259 v\u0259 erk\u0259n m\u0259rh\u0259l\u0259l\u0259rd\u0259 çürükl\u0259rin inki\u015faf\u0131n\u0131 l\u0259ngid\u0259 bil\u0259c\u0259yini a\u015fkar etdil\u0259r. Bu bar\u0259d\u0259 a\u011f\u0131z x\u0259st\u0259likl\u0259rinin qar\u015f\u0131s\u0131n\u0131n al\u0131nmas\u0131 il\u0259 ba\u011fl\u0131 yeni m\u0259lumatlara h\u0259sr olunmu\u015f bir n\u0259\u015frd\u0259 m\u0259lumat verilib.<\/strong><\/p>\n

Ucnoqta.az x\u0259b\u0259r verir ki, çürükl\u0259r a\u011f\u0131zda ya\u015fayan bakteriyalar\u0131n f\u0259aliyy\u0259ti n\u0259tic\u0259sind\u0259 \u0259m\u0259l\u0259 g\u0259lir. Bu mikroorqanizml\u0259r qidadan \u015f\u0259k\u0259rl\u0259ri emal edir v\u0259 di\u015f minas\u0131n\u0131 t\u0259dric\u0259n m\u0259hv ed\u0259n tur\u015fular ifraz edir. Zamanla bakteriyalar tur\u015fu mühitinin daha uzun müdd\u0259t qald\u0131\u011f\u0131 v\u0259 s\u0259rt di\u015f toxumas\u0131na ziyan\u0131 art\u0131rd\u0131\u011f\u0131 s\u0131x biofilml\u0259r – di\u015f lövh\u0259si \u0259m\u0259l\u0259 g\u0259tirir.<\/p>\n

Aliml\u0259r öz i\u015fl\u0259rind\u0259 arginin bu biofilml\u0259rin xüsusiyy\u0259tl\u0259rini d\u0259yi\u015fdir\u0259 bil\u0259c\u0259yini a\u015fkar etdil\u0259r. Faydal\u0131 mikroorqanizml\u0259r bu amin tur\u015fusundan tur\u015fular\u0131 neytralla\u015fd\u0131ran q\u0259l\u0259vi birl\u0259\u015fm\u0259l\u0259r \u0259m\u0259l\u0259 g\u0259tirm\u0259k üçün istifad\u0259 edirl\u0259r. A\u011f\u0131zda yüks\u0259k arginin s\u0259viyy\u0259si qoruyucu bakteriyalar üçün \u0259lveri\u015fli bir mühit yarad\u0131r, tur\u015fu istehsal ed\u0259n növl\u0259r is\u0259 t\u0259dric\u0259n dominantl\u0131\u011f\u0131n\u0131 itirir.<\/p>\n

Bu t\u0259siri praktikada s\u0131naqdan keçirm\u0259k üçün Orhus Universitetinin professoru Sebastian \u015elaferin r\u0259hb\u0259rlik etdiyi bir qrup, aktiv di\u015f çürükl\u0259ri diaqnozu qoyulmu\u015f 12 x\u0259st\u0259ni \u0259hat\u0259 ed\u0259n klinik bir ara\u015fd\u0131rma apard\u0131. \u0130\u015ftirakç\u0131lar ç\u0259n\u0259nin müxt\u0259lif nahiy\u0259l\u0259rind\u0259n bütöv di\u015f biofilml\u0259rini toplama\u011fa imkan ver\u0259n xüsusi ç\u0131xar\u0131la bil\u0259n cihazlardan istifad\u0259 etdil\u0259r. Biofilml\u0259ri \u015f\u0259k\u0259r m\u0259hlulu il\u0259 müalic\u0259 etdikd\u0259n sonra bir hiss\u0259si argininl\u0259, dig\u0259r hiss\u0259si is\u0259 neytral madd\u0259 il\u0259 t\u0259masda olub.<\/p>\n

N\u0259tic\u0259l\u0259r göst\u0259rib ki, argininl\u0259 müalic\u0259 olunan nahiy\u0259l\u0259r \u015f\u0259k\u0259rl\u0259 t\u0259masdan 10 v\u0259 35 d\u0259qiq\u0259 sonra bel\u0259 daha yüks\u0259k pH s\u0259viyy\u0259sini saxlay\u0131r. Bu, daha az tur\u015fulu mühitin v\u0259 n\u0259tic\u0259d\u0259 minan\u0131n z\u0259d\u0259l\u0259nm\u0259 riskinin daha a\u015fa\u011f\u0131 oldu\u011funu göst\u0259rir. Bundan \u0259lav\u0259, t\u0259hlil lövh\u0259 strukturunda d\u0259yi\u015fiklikl\u0259r a\u015fkar etdi: lokal "tur\u015fu zonalar\u0131n\u0131n" \u0259m\u0259l\u0259 g\u0259lm\u0259sin\u0259 köm\u0259k ed\u0259n karbohidratlar\u0131n t\u0259rkibi azal\u0131b v\u0259 \u015f\u0259k\u0259rl\u0259rin paylanmas\u0131 di\u015f s\u0259thin\u0259 daha az z\u0259r\u0259rli olub.<\/p>\n

Mikrofloran\u0131n genetik t\u0259dqiqat\u0131 balans\u0131n arginin metabolizmas\u0131na v\u0259 daha neytral a\u011f\u0131z mühitini saxlama\u011fa qadir olan bakteriyalara do\u011fru d\u0259yi\u015fdiyini t\u0259sdiql\u0259yib. T\u0259dqiqat mü\u0259llifl\u0259rin\u0259 gör\u0259, arginin b\u0259d\u0259nin t\u0259hlük\u0259siz v\u0259 t\u0259bii bir komponentidir v\u0259 bir çox qidada da mövcuddur. Bu, onu kariyesin qar\u015f\u0131s\u0131n\u0131 almaq üçün perspektivli bir vasit\u0259y\u0259 çevirir.
\nAliml\u0259r hesab edirl\u0259r ki, di\u015f m\u0259cunlar\u0131na v\u0259 a\u011f\u0131z yaxalay\u0131c\u0131lar\u0131na arginin \u0259lav\u0259 etm\u0259k, xüsus\u0259n d\u0259 u\u015faqlar da daxil olmaqla, kariyesin inki\u015faf riski yüks\u0259k olan insanlar üçün t\u0259sirli qoruyucu t\u0259dbir ola bil\u0259r. Eyni zamanda, müt\u0259x\u0259ssisl\u0259r h\u0259r k\u0259s\u0259 xat\u0131rlad\u0131r ki, a\u011f\u0131z sa\u011flaml\u0131\u011f\u0131na diqq\u0259t yetirilm\u0259lidir: di\u015f \u0259rpind\u0259ki d\u0259yi\u015fiklikl\u0259r, xo\u015fag\u0259lm\u0259z qoxu v\u0259 ya narahatl\u0131q di\u015f h\u0259kimi il\u0259 m\u0259sl\u0259h\u0259tl\u0259\u015fm\u0259 t\u0259l\u0259b ed\u0259n probleml\u0259rin siqnal\u0131 ola bil\u0259r.<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u0259dqiqatç\u0131lar insan tüpürc\u0259yind\u0259 olan t\u0259bii amin tur\u015fusu olan arginin di\u015f lövh\u0259sinin aqressiv xüsusiyy\u0259tl\u0259rini z\u0259ifl\u0259d\u0259 v\u0259 erk\u0259n m\u0259rh\u0259l\u0259l\u0259rd\u0259 çürükl\u0259rin inki\u015faf\u0131n\u0131 l\u0259ngid\u0259 bil\u0259c\u0259yini a\u015fkar etdil\u0259r. Bu bar\u0259d\u0259 a\u011f\u0131z x\u0259st\u0259likl\u0259rinin qar\u015f\u0131s\u0131n\u0131n al\u0131nmas\u0131 il\u0259…<\/p>\n","protected":false},"author":1,"featured_media":251278,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[100],"tags":[],"class_list":["post-236998","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-diger"],"_links":{"self":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts\/236998","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=236998"}],"version-history":[{"count":0,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts\/236998\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/media\/251278"}],"wp:attachment":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=236998"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=236998"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=236998"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}