{"id":236508,"date":"2026-01-07T06:15:01","date_gmt":"2026-01-07T02:15:01","guid":{"rendered":""},"modified":"-0001-11-30T00:00:00","modified_gmt":"-0001-11-29T20:00:00","slug":"","status":"publish","type":"post","link":"https:\/\/ucnoqta.az\/?p=236508","title":{"rendered":"Ana h\u00fcceyr\u0259l\u0259rinin insan b\u0259d\u0259nind\u0259 \u00f6m\u00fcrl\u00fck qalmas\u0131n\u0131n s\u0259b\u0259bi"},"content":{"rendered":"

Yetkin insan b\u0259d\u0259nind\u0259 ana hüceyr\u0259l\u0259rinin olmas\u0131 uzun müdd\u0259t elmi sirr olaraq qal\u0131b. Ax\u0131 immun sistemi yad olan h\u0259r \u015feyi m\u0259hv etm\u0259k üçün n\u0259z\u0259rd\u0259 tutulub. Lakin bu hüceyr\u0259l\u0259r \u0259ks\u0259r insanlarda patoloji reaksiyalara s\u0259b\u0259b olmadan n\u0259inki sa\u011f qal\u0131r, h\u0259m d\u0259 ömür boyu davam edir. <\/strong><\/p>\n

Ucnoqta.az x\u0259b\u0259r verir ki, son t\u0259dqiqatlar bu t\u0259\u0259ccüblü fenomeni i\u015f\u0131qland\u0131r\u0131r.<\/p>\n

\u0130mmunoloqlar qrupu genetik modifikasiya olunmu\u015f siçanlar üz\u0259rind\u0259 bir s\u0131ra t\u0259crüb\u0259l\u0259r apar\u0131b. D\u0259yi\u015fdirilmi\u015f immun hüceyr\u0259l\u0259ri olan heyvanlardan istifad\u0259 ed\u0259r\u0259k t\u0259dqiqatç\u0131lar mü\u0259yy\u0259n hüceyr\u0259 populyasiyalar\u0131n\u0131 d\u0259qiq izl\u0259y\u0259 v\u0259 selektiv \u015f\u0259kild\u0259 ç\u0131xara bilibl\u0259r. Bu, onlara ana v\u0259 q\u0131z hüceyr\u0259l\u0259ri aras\u0131ndak\u0131 qar\u015f\u0131l\u0131ql\u0131 t\u0259sirl\u0259ri \u0259trafl\u0131 öyr\u0259nm\u0259y\u0259 imkan verib.<\/p>\n

T\u0259dqiqat\u0131n n\u0259tic\u0259l\u0259ri göst\u0259rib ki, do\u011fu\u015fdan sonra n\u0259sild\u0259 yaln\u0131z kiçik bir ana immun hüceyr\u0259l\u0259ri qrupu qal\u0131r. Bu hüceyr\u0259l\u0259r öz xüsusiyy\u0259tl\u0259rin\u0259 gör\u0259 sümük iliyinin miyeloid hüceyr\u0259l\u0259rin\u0259 v\u0259 dendritik hüceyr\u0259l\u0259r\u0259 b\u0259nz\u0259yir. Onlar\u0131n rolu çox vacib oldu\u011funu sübut edib – onlar birba\u015fa immun sisteminin aktivl\u0259\u015fm\u0259si il\u0259 ba\u011fl\u0131d\u0131r v\u0259 t\u0259nziml\u0259yici T hüceyr\u0259l\u0259rinin böyüm\u0259sini stimulla\u015fd\u0131r\u0131r.<\/p>\n

T\u0259nziml\u0259yici T hüceyr\u0259l\u0259ri immun balans\u0131n\u0131 qorumaqdan, b\u0259d\u0259nin öz hüceyr\u0259l\u0259rin\u0259 qar\u015f\u0131 aqressiv immun reaksiyas\u0131n\u0131n qar\u015f\u0131s\u0131n\u0131 almaqdan m\u0259suldur. T\u0259crüb\u0259 onlar\u0131n ana hüceyr\u0259l\u0259rind\u0259n as\u0131l\u0131l\u0131\u011f\u0131n\u0131 t\u0259sdiql\u0259di: sonuncu siçanlardan süni \u015f\u0259kild\u0259 ç\u0131xar\u0131ld\u0131qdan sonra t\u0259nziml\u0259yici T hüceyr\u0259l\u0259ri yox oldu v\u0259 b\u0259d\u0259nin ana hüceyr\u0259l\u0259rin\u0259 dözm\u0259k qabiliyy\u0259ti itirildi.<\/p>\n

Bu tap\u0131nt\u0131lar immun sisteminin nec\u0259 f\u0259aliyy\u0259t göst\u0259rdiyin\u0259 dair anlay\u0131\u015f\u0131m\u0131z\u0131 kökünd\u0259n d\u0259yi\u015fdirir. M\u0259lum olur ki, tarazl\u0131\u011f\u0131 qorumaq üçün az sayda yad hüceyr\u0259nin daimi olmas\u0131 t\u0259l\u0259b olunur. Onlar\u0131n ç\u0131xar\u0131lmas\u0131 aqressiv immun davran\u0131\u015f\u0131na s\u0259b\u0259b olur ki, bu da müxt\u0259lif x\u0259st\u0259likl\u0259rin inki\u015faf\u0131na s\u0259b\u0259b ola bil\u0259r.
\nBu k\u0259\u015ff klinik t\u0259crüb\u0259 üçün \u0259h\u0259miyy\u0259tli potensiala malikdir. <\/p>\n","protected":false},"excerpt":{"rendered":"

Yetkin insan b\u0259d\u0259nind\u0259 ana hüceyr\u0259l\u0259rinin olmas\u0131 uzun müdd\u0259t elmi sirr olaraq qal\u0131b. Ax\u0131 immun sistemi yad olan h\u0259r \u015feyi m\u0259hv etm\u0259k üçün n\u0259z\u0259rd\u0259 tutulub. Lakin bu hüceyr\u0259l\u0259r \u0259ks\u0259r insanlarda patoloji…<\/p>\n","protected":false},"author":1,"featured_media":251278,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[100],"tags":[],"class_list":["post-236508","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-diger"],"_links":{"self":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts\/236508","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=236508"}],"version-history":[{"count":0,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts\/236508\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/media\/251278"}],"wp:attachment":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=236508"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=236508"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=236508"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}