{"id":231700,"date":"2025-10-09T07:30:10","date_gmt":"2025-10-09T03:30:10","guid":{"rendered":""},"modified":"-0001-11-30T00:00:00","modified_gmt":"-0001-11-29T20:00:00","slug":"","status":"publish","type":"post","link":"https:\/\/ucnoqta.az\/?p=231700","title":{"rendered":"117 il ya\u015fayan qad\u0131n\u0131n uzun\u00f6m\u00fcrl\u00fcl\u00fcy\u00fcn\u00fcn sirri a\u00e7\u0131l\u0131b"},"content":{"rendered":"

Müt\u0259x\u0259ssisl\u0259r 117 ya\u015fl\u0131 Maria Brañas Moreran\u0131n genetik material\u0131n\u0131 t\u0259dqiq ed\u0259r\u0259k gözl\u0259nilm\u0259z m\u0259lumatlar \u0259ld\u0259 edibl\u0259r. T\u0259hlil qocalman\u0131n adi anlay\u0131\u015f\u0131na zidd olan nümun\u0259ni a\u015fkara ç\u0131xar\u0131b. <\/strong><\/p>\n

Ucnoqta.az x\u0259b\u0259r verir ki, t\u0259dqiqat onun bir \u0259srd\u0259n çox ya\u015faya bildiyini v\u0259 zehni ayd\u0131nl\u0131\u011f\u0131n\u0131 nec\u0259 qorudu\u011funu izah edir.<\/p>\n

Mariya 4 mart 1907-ci ild\u0259 AB\u015e-da anadan olub. Onun s\u0259kkiz ya\u015f\u0131 olanda ail\u0259si \u0130spaniyaya köçüb. Daha sonra o, Azor adalar\u0131 v\u0259 Kuba il\u0259 uzun d\u0259niz s\u0259yah\u0259tini xat\u0131rlad\u0131, bu da müharib\u0259 dövrünün m\u0259hdudiyy\u0259tl\u0259ri il\u0259 \u0259laq\u0259dard\u0131r.
\n24 ya\u015f\u0131nda Brañas h\u0259kim Joan Moret il\u0259 evl\u0259nib. V\u0259t\u0259nda\u015f müharib\u0259si zaman\u0131 cütlük Trujillodak\u0131 s\u0259hra x\u0259st\u0259xanas\u0131nda i\u015fl\u0259yirdi: o, yaral\u0131lar\u0131 müalic\u0259 etdi, tibb bac\u0131s\u0131 kimi köm\u0259k edib.<\/p>\n

Onlar dörd onillik birlikd\u0259 ya\u015fay\u0131blar. Ail\u0259nin üç övlad\u0131, 11 n\u0259v\u0259si v\u0259 13 n\u0259tic\u0259si olub. 1976-c\u0131 ild\u0259 Mariya dul qald\u0131 v\u0259 bir müdd\u0259t sonra yegan\u0259 o\u011flunu itirdi.
\nZaman keçdikc\u0259 a\u011f\u0131r itkil\u0259r azald\u0131. 1990-c\u0131 ill\u0259rd\u0259 Brañas s\u0259yah\u0259t\u0259 ba\u015flad\u0131, \u0130taliya, \u0130ngilt\u0259r\u0259, Misir v\u0259 Hollandiyaya ba\u015f ç\u0259kdi. Onun hobbil\u0259rin\u0259 kitab oxumaq, tiki\u015f tikm\u0259k v\u0259 musiqi daxildir. Barselonada Liseu Konservatoriyas\u0131nda t\u0259hsil al\u0131b v\u0259 pianoda ifa edib.<\/p>\n

\u0130ll\u0259r keçdikc\u0259 Maria yeni texnologiyalara da maraq göst\u0259rdi. Yetkinlik dövründ\u0259 o, sosial median\u0131 m\u0259nims\u0259di v\u0259 Twitter-d\u0259 (indi X) aktiv \u015f\u0259kild\u0259 ünsiyy\u0259t qurdu. 2019-cu ild\u0259 La Vanguardia il\u0259 müsahib\u0259sind\u0259 o, h\u0259yat\u0131 boyu c\u0259miyy\u0259td\u0259 ba\u015f ver\u0259n d\u0259yi\u015fiklikl\u0259ri müzakir\u0259 etdi.<\/p>\n

113 ya\u015f\u0131nda o, COVID-19-dan sa\u011fald\u0131 v\u0259 sa\u011falma\u011f\u0131 bacard\u0131. H\u0259yat\u0131n\u0131n son onillikl\u0259rind\u0259 o, qocalar evind\u0259 ya\u015fay\u0131rd\u0131, burada aktiv olaraq qal\u0131r v\u0259 g\u0259nc qon\u015fular\u0131ndan f\u0259rql\u0259nirdi. E\u015fitm\u0259 v\u0259 h\u0259r\u0259k\u0259t qabiliyy\u0259ti pisl\u0259\u015fs\u0259 d\u0259, demensiya v\u0259 depressiya ona toxunmad\u0131.<\/p>\n

2024-cü ilin yay\u0131nda Maria sonunun yax\u0131nla\u015fd\u0131\u011f\u0131n\u0131 hiss etdi v\u0259 sevdikl\u0259ri üçün vida mesaj\u0131 buraxd\u0131. O, h\u0259min il avqustun 19-da 117 ya\u015f 168 gün ya\u015f\u0131nda v\u0259fat edib.
\nGenetik bir sir<\/strong>
\nT\u0259dqiqat m\u0259lumatlar\u0131 onun 116 ya\u015f\u0131 olanda toplan\u0131b. Onlar biorxiv.org sayt\u0131nda d\u0259rc olunan "\u0130nsan ömrünün h\u0259ddind\u0259n art\u0131q olmas\u0131 üçün multi-omiks ç\u0259rçiv\u0259si" adl\u0131 m\u0259qal\u0259d\u0259 istifad\u0259 edilib. Aliml\u0259r qocalman\u0131 yava\u015flatman\u0131n açar\u0131n\u0131 tapma\u011fa ümid edirdil\u0259r, lakin n\u0259tic\u0259 f\u0259rqli oldu. Branyas\u0131n bioloji ya\u015f\u0131 90-\u0131 keçm\u0259yib. B\u0259d\u0259ni qocalma prosesini kompensasiya ed\u0259r\u0259k sa\u011flaml\u0131\u011f\u0131n\u0131 qoruyub saxlama\u011fa imkan verib.<\/p>\n

T\u0259dqiqatç\u0131lar xüsusil\u0259 telomerl\u0259r\u0259 diqq\u0259t yetiribl\u0259r. Onlar ad\u0259t\u0259n ya\u015fla q\u0131sal\u0131r v\u0259 hüceyr\u0259l\u0259ri h\u0259ssas edir. Marian\u0131n v\u0259ziyy\u0259tind\u0259 is\u0259 onlar \u0259h\u0259miyy\u0259tli d\u0259r\u0259c\u0259d\u0259 tük\u0259nmi\u015fdil\u0259r ki, bu da x\u0259rç\u0259ng hüceyr\u0259l\u0259rinin inki\u015faf\u0131na mane ola bil\u0259rdi.<\/p>\n

Bununla bel\u0259, heç bir “ölümsüzlük geni” mü\u0259yy\u0259n edilm\u0259mi\u015fdir. Aliml\u0259r bel\u0259 q\u0259na\u0259t\u0259 g\u0259libl\u0259r ki, nadir genetik variantlar\u0131n v\u0259 bioloji mexanizml\u0259rin birl\u0259\u015fm\u0259si onun uzunömürlü olmas\u0131na köm\u0259k edib.<\/p>\n

Onun immun sistemi eyni d\u0259r\u0259c\u0259d\u0259 paradoksal idi. Qad\u0131n b\u0259d\u0259nin müdafi\u0259sini t\u0259min ed\u0259n v\u0259 immun yadda\u015f\u0131 d\u0259st\u0259kl\u0259y\u0259n T- v\u0259 B-hüceyr\u0259l\u0259rini yüks\u0259k s\u0259viyy\u0259d\u0259 saxlay\u0131b. Ba\u011f\u0131rsaqlarda çoxlu sayda faydal\u0131 bakteriyalar\u0131n olmas\u0131 qocalman\u0131n \u0259sas faktoru say\u0131lan sistemli iltihab\u0131n qar\u015f\u0131s\u0131n\u0131 al\u0131b.
\nMüt\u0259x\u0259ssisl\u0259r Branyas\u0131n hüceyr\u0259l\u0259rinin daha g\u0259nc bir insan\u0131n hüceyr\u0259l\u0259ri kimi f\u0259aliyy\u0259t göst\u0259rdiyini qeyd edibl\u0259r. Mariya uzunömürlülüyünü sad\u0259 prinsipl\u0259rl\u0259 \u0259laq\u0259l\u0259ndirdi: nizam-intizam, sakitlik, ail\u0259 il\u0259 yax\u015f\u0131 münasib\u0259tl\u0259r, t\u0259bi\u0259t\u0259 yax\u0131nl\u0131q, müsb\u0259t dünyagörü\u015fü v\u0259 insanlarla m\u0259nfi münasib\u0259td\u0259n qaç\u0131nmaq.<\/p>\n","protected":false},"excerpt":{"rendered":"

Müt\u0259x\u0259ssisl\u0259r 117 ya\u015fl\u0131 Maria Brañas Moreran\u0131n genetik material\u0131n\u0131 t\u0259dqiq ed\u0259r\u0259k gözl\u0259nilm\u0259z m\u0259lumatlar \u0259ld\u0259 edibl\u0259r. T\u0259hlil qocalman\u0131n adi anlay\u0131\u015f\u0131na zidd olan nümun\u0259ni a\u015fkara ç\u0131xar\u0131b.  Ucnoqta.az x\u0259b\u0259r verir ki, t\u0259dqiqat onun bir…<\/p>\n","protected":false},"author":1,"featured_media":251278,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[97],"tags":[],"class_list":["post-231700","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-maraqli"],"_links":{"self":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts\/231700","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=231700"}],"version-history":[{"count":0,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts\/231700\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/media\/251278"}],"wp:attachment":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=231700"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=231700"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=231700"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}