{"id":231024,"date":"2025-09-29T07:02:55","date_gmt":"2025-09-29T03:02:55","guid":{"rendered":""},"modified":"-0001-11-30T00:00:00","modified_gmt":"-0001-11-29T20:00:00","slug":"","status":"publish","type":"post","link":"https:\/\/ucnoqta.az\/?p=231024","title":{"rendered":"Xroniki yuxusuzlu\u011fun s\u0259b\u0259b oldu\u011fu"},"content":{"rendered":"

Mayo Klinikas\u0131ndan olan amerikal\u0131 t\u0259dqiqatç\u0131lar ya\u015fl\u0131 insanlarda xroniki yuxusuzluq v\u0259 demans riskini art\u0131ran beyin d\u0259yi\u015fiklikl\u0259ri aras\u0131nda \u0259laq\u0259 tap\u0131blar. <\/strong><\/p>\n

Ucnoqta.az x\u0259b\u0259r verir ki, t\u0259dqiqat ya\u015f\u0131 50 v\u0259 daha yuxar\u0131 olan 2750 i\u015ftirakç\u0131n\u0131 orta hesabla be\u015f il yar\u0131m izl\u0259di.
\nH\u0259r il könüllül\u0259r yadda\u015f testl\u0259rind\u0259n, b\u0259zil\u0259ri is\u0259 koqnitiv poz\u011funlu\u011fun iki \u0259sas markerini qiym\u0259tl\u0259ndirm\u0259k üçün beyin skan\u0131ndan keçibl\u0259r: amiloid lövh\u0259l\u0259ri v\u0259 a\u011f madd\u0259nin hiperintensiyas\u0131.<\/p>\n

Xroniki yuxusuzluq bir ay \u0259rzind\u0259 \u0259n az\u0131 iki d\u0259f\u0259 qeyd\u0259 al\u0131nan yuxusuzluq kimi mü\u0259yy\u0259n edilib. Bu diaqnozu i\u015ftirakç\u0131lar\u0131n 16%-i q\u0259bul edib. Xroniki yuxusuzlu\u011fu olan insanlar yadda\u015f v\u0259 t\u0259f\u0259kkürd\u0259 daha sür\u0259tli bir azalma göst\u0259rdil\u0259r v\u0259 onlar\u0131n yüngül idrak poz\u011funlu\u011fu v\u0259 ya demans riski sa\u011flam yatm\u0131\u015f i\u015ftirakç\u0131larla müqayis\u0259d\u0259 40% daha yüks\u0259k olub.<\/p>\n

T\u0259siri adi haldan az yatanlarda xüsusil\u0259 n\u0259z\u0259r\u0259 çarp\u0131rd\u0131. Art\u0131q ilk qiym\u0259tl\u0259ndirm\u0259d\u0259, bu \u015f\u0259xsl\u0259rin beyinl\u0259rind\u0259 t\u0259xmin\u0259n dörd il sonra qocalma \u0259lam\u0259tl\u0259ri mü\u015fahid\u0259 edildi: amiloid s\u0259viyy\u0259l\u0259rinin yüks\u0259lm\u0259si v\u0259 a\u011f madd\u0259nin daha çox z\u0259d\u0259l\u0259nm\u0259si. H\u0259mi\u015f\u0259kind\u0259n daha çox yatanlarda bu lezyonlardan daha az rast g\u0259linir.
\nAmiloid lövh\u0259l\u0259ri neyronlar\u0131 ba\u011flay\u0131r, a\u011f madd\u0259 lezyonlar\u0131 is\u0259 beyin bölg\u0259l\u0259ri aras\u0131nda siqnal ötürülm\u0259sini pozur. Xroniki yuxusuzluqdan \u0259ziyy\u0259t ç\u0259k\u0259n insanlarda bu markerl\u0259rin birg\u0259 olmas\u0131 yuxusuzlu\u011fun beyind\u0259 “ikiqat t\u0259la\u015f” yaratd\u0131\u011f\u0131n\u0131 t\u0259sdiql\u0259yir.<\/p>\n

Xroniki yuxusuzlu\u011fun t\u0259siri gec ba\u015flayan Alzheimer x\u0259st\u0259liyi üçün \u0259n güclü ümumi genetik risk faktoru olan ApoE4 geninin t\u0259siri il\u0259 müqayis\u0259 edil\u0259 bil\u0259rdi. Genin da\u015f\u0131y\u0131c\u0131lar\u0131 idrak funksiyas\u0131nda daha sür\u0259tli azalma nümayi\u015f etdirdil\u0259r v\u0259 yuxusuzluq amiloid klirensini yava\u015flataraq v\u0259 damarlar\u0131n iltihaba h\u0259ssasl\u0131\u011f\u0131n\u0131 art\u0131raraq z\u0259r\u0259ri daha da art\u0131rd\u0131.<\/p>\n

T\u0259dqiqat\u0131n n\u0259tic\u0259l\u0259ri Böyük Britaniya, Çin v\u0259 AB\u015e-da orta ya\u015fda v\u0259 ondan k\u0259narda yuxu keyfiyy\u0259tinin h\u0259yat\u0131n sonrak\u0131 dövrl\u0259rind\u0259 koqnitiv performansla s\u0131x ba\u011fl\u0131 oldu\u011funu göst\u0259r\u0259n \u0259vv\u0259lki t\u0259dqiqatlarla uy\u011fun g\u0259lir. Xroniki yuxusuzluq beyn\u0259 müxt\u0259lif yollarla t\u0259sir edir: amiloidl\u0259rin y\u0131\u011f\u0131lmas\u0131, a\u011f madd\u0259nin z\u0259d\u0259l\u0259nm\u0259si v\u0259 qan t\u0259zyiqi v\u0259 qan \u015f\u0259k\u0259ri s\u0259viyy\u0259l\u0259rind\u0259 mümkün art\u0131mlar.
\nAliml\u0259r yuxu h\u0259bl\u0259rinin birba\u015fa faydas\u0131 v\u0259 ya z\u0259r\u0259ri tapmay\u0131blar. Oreksin blokerl\u0259ri d\u0259 daxil olmaqla daha yeni d\u0259rmanlar, Alzheimer x\u0259st\u0259liyi il\u0259 \u0259laq\u0259li zülallar\u0131n s\u0259viyy\u0259sin\u0259 yaln\u0131z q\u0131samüdd\u0259tli t\u0259sir göst\u0259rmi\u015fdir. Yuxusuzluq üçün koqnitiv davran\u0131\u015f terapiyas\u0131, ist\u0259r \u015f\u0259xs\u0259n, ist\u0259rs\u0259 d\u0259 r\u0259q\u0259msal olaraq, x\u0259st\u0259l\u0259rin t\u0259xmin\u0259n 70%-d\u0259 yuxunu yax\u015f\u0131la\u015fd\u0131r\u0131r. Kiçik bir ara\u015fd\u0131rma, dan\u0131\u015f\u0131q terapiyas\u0131ndan sonra yüngül idrak poz\u011funlu\u011fu olan insanlarda icra funksiyalar\u0131n\u0131n yax\u015f\u0131la\u015fd\u0131\u011f\u0131n\u0131 tapd\u0131.
\n50 ya\u015f\u0131nda gec\u0259 alt\u0131 saatdan az yatmaq 20 il sonra demans riskini art\u0131r\u0131r v\u0259 bu, t\u0259qaüd\u0259 ç\u0131xmazdan \u0259vv\u0259l qar\u015f\u0131s\u0131n\u0131n al\u0131nmas\u0131n\u0131n vacibliyini vur\u011fulay\u0131r. Qan t\u0259zyiqi, xolesterol s\u0259viyy\u0259l\u0259ri v\u0259 fiziki f\u0259aliyy\u0259tl\u0259 birlikd\u0259 yuxunun idar\u0259 edilm\u0259si beyin sa\u011flaml\u0131\u011f\u0131 üçün vacib strategiya hesab olunur.
\nXroniki yuxusuzluq amiloidl\u0259rin y\u0131\u011f\u0131lmas\u0131n\u0131 v\u0259 damarlar\u0131n z\u0259d\u0259l\u0259nm\u0259sini sür\u0259tl\u0259ndirir, xüsusil\u0259 ApoE4 geninin da\u015f\u0131y\u0131c\u0131lar\u0131nda koqnitiv funksiyan\u0131 azald\u0131r. Keyfiyy\u0259tli yuxu beyin sa\u011flaml\u0131\u011f\u0131nda \u0259sas d\u0259yi\u015fdiril\u0259 bil\u0259n amil hesab edilir, lakin yuxusuzlu\u011fa müdaxil\u0259nin demans\u0131n qar\u015f\u0131s\u0131n\u0131n al\u0131nmas\u0131na t\u0259siri v\u0259 müdaxil\u0259nin optimal vaxt\u0131 h\u0259l\u0259 d\u0259 öyr\u0259nilir.<\/p>\n","protected":false},"excerpt":{"rendered":"

Mayo Klinikas\u0131ndan olan amerikal\u0131 t\u0259dqiqatç\u0131lar ya\u015fl\u0131 insanlarda xroniki yuxusuzluq v\u0259 demans riskini art\u0131ran beyin d\u0259yi\u015fiklikl\u0259ri aras\u0131nda \u0259laq\u0259 tap\u0131blar.  Ucnoqta.az x\u0259b\u0259r verir ki, t\u0259dqiqat ya\u015f\u0131 50 v\u0259 daha yuxar\u0131 olan 2750…<\/p>\n","protected":false},"author":1,"featured_media":251278,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[],"tags":[],"class_list":["post-231024","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts\/231024","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=231024"}],"version-history":[{"count":0,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/posts\/231024\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=\/wp\/v2\/media\/251278"}],"wp:attachment":[{"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=231024"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=231024"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/ucnoqta.az\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=231024"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}